Opportunistic Scheduling and Beamforming for MIMO-OFDMA Downlink Systems with Reduced Feedback

Opportunistic scheduling and beamforming schemes with reduced feedback are proposed for MIMO-OFDMA downlink systems. Unlike the conventional beamforming schemes in which beamforming is implemented solely by the base station (BS) in a per-subcarrier fashion, the proposed schemes take advantages of a novel channel decomposition technique to perform beamforming jointly by the BS and the mobile terminal (MT). The resulting beamforming schemes allow the BS to employ only {\em one} beamforming matrix (BFM) to form beams for {\em all} subcarriers while each MT completes the beamforming task for each subcarrier locally. Consequently, for a MIMO-OFDMA system with $Q$ subcarriers, the proposed opportunistic scheduling and beamforming schemes require only one BFM index and $Q$ supportable throughputs to be returned from each MT to the BS, in contrast to $Q$ BFM indices and $Q$ supportable throughputs required by the conventional schemes. The advantage of the proposed schemes becomes more evident when a further feedback reduction is achieved by grouping adjacent subcarriers into exclusive clusters and returning only cluster information from each MT. Theoretical analysis and computer simulation confirm the effectiveness of the proposed reduced-feedback schemes.Comment: Proceedings of the 2008 IEEE International Conference on Communications, Beijing, May 19-23, 200

QRD-QLD searching based sphere detection for emerging MIMO downlink OFDM receivers

In this paper, a detection algorithm with parallel partial candidate-search algorithm is presented. Two fully independent partial search processes are simultaneously employed for two groups of transmit antennas based on QR and QL decompositions of the channel matrix. Proposed QRDQLD detection algorithm is compared with well-known QRD-M scheme adopted for several emerging wireless standards. Latency of the QRD-QLD candidate search is about twice as small for similar error-rate performance and for identical hardware resources. Total detection latency of QRD-QLD algorithm that also includes computation of soft information for outer decoder is also substantially smaller.Nokia CorporationNational Science Foundatio

Parallel Searching-Based Sphere Detector for MIMO Downlink OFDM Systems

In this paper, implementation of a detector with parallel partial candidate-search algorithm is described. Two fully independent partial candidate search processes are simultaneously employed for two groups of transmit antennas based on QR decomposition (QRD) and QL decomposition (QLD) of a multiple-input multiple-output (MIMO) channel matrix. By using separate simultaneous candidate searching processes, the proposed implementation of QRD-QLD searching-based sphere detector provides a smaller latency and a lower computational complexity than the original QRD-M detector for similar error-rate performance in wireless communications systems employing four transmit and four receive antennas with 16-QAM or 64-QAM constellation size. It is shown that in coded MIMO orthogonal frequency division multiplexing (MIMO OFDM) systems, the detection latency and computational complexity of a receiver can be substantially reduced by using the proposed QRD-QLD detector implementation. The QRD-QLD-based sphere detector is also implemented using Field Programmable Gate Array (FPGA) and application specific integrated circuit (ASIC), and its hardware design complexity is compared with that of other sphere detectors reported in the literature.Nokia Renesas MobileTexas InstrumentsXilinxNational Science Foundatio

Solution structures of RseA and its complex with RseB

Conformational changes of RseA and RseB were observed by circular dichroism and small-angle X-ray scattering upon the formation of their complex

RNA-Guided Genome Editing in Drosophila with the Purified Cas9 Protein

We report a method for generating Drosophila germline mutants effectively via injection of the complex of the purified Cas9 protein, tracrRNA, and gene-specific crRNAs, which may reduce delayed mutations because of the transient activity of the Cas9 protein, combined with the simple mutation detection in GO founders by the T7E1 assay.

CD4+ T cells from MHC II-dependent thymocyte–thymocyte interaction provide efficient help for B cells

Recently, a novel CD4+ T-cell developmental pathway was reported that generates thymocyte–thymocyte (T–T) CD4+ T cells. We established a mouse system (CIITAtgCIITApIV−/−) where thymic positive selection occurred only by major histocompatibility complex (MHC) class II+ thymocytes. T–T CD4+ T cells selected via MHC class II-dependent T–T interaction are comprised of PLZF-negative and innate PLZF-positive populations. Until recently, the functional role of the PLZF-negative population was unclear. In this study, we demonstrate that naïve T–T CD4+ T cells provide B-cell help to a level comparable with that of naïve conventional CD4+ T cells. Considering the absence of PLZF expression in naïve T–T CD4+ T cells, these results suggest that PLZF-negative naïve T–T CD4+ T cells are functionally equivalent to conventional naïve CD4+ T cells in terms of B-cell help